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27-30 June 2007 Helsinki, Finland The 46th ESPE annual meeting was the largest annual meeting to date with over 2200 delegates. The Finnish Minister of Health warmly welcomed delegates; this was followed by greetings from Professor Raimo Voutilainen (Kuopio, Finland) 2007 ESPE President. We were reminded that the last time the ESPE annual meeting was held in Helsinki was in 1982. During the past 25 years there have been enormous changes in Europe, not least the easing of Cold War tensions, a process precipitated in part by the Helsinki Accords. It is under this climate of free trade and free exchange of ideas that delegates from 87 different countries came to ESPE 2007. The social activity of the Nordic Walk was inspired by the conference theme of 'Prevention of endocrine disorders and their long-term sequelae'. The delegate bag was also avidly discussed - a black and white spotted bag designed by Marimekko, and (possibly) inspired by the film '101 Dalmatians'. For the duration of ESPE 2007 the scientific discourse of the meeting showed no sign of abating. Even after a long day concentrating at session after session, large numbers of participants attended the social events to engage in recreation, which met with universal approval. Our focus on science was, in part, helped by rainy and cold weather, which ensured that distractions were kept to minimum and that large numbers of delegates attended all sessions. The 'Meet the Experts' sessions proved very popular and were well attended. The Helsinki Fair Centre proved to be an excellent conference venue with the delegates enjoying the spacious layout to move between sessions, ensuing a very successful conference
The most important ESPE awards and prizes are the Andrea Prader Prize, the Research Award, the Outstanding Clinician Award and the Young Investigator Award. These awards and prizes are kindly supported by Pfizer through an unrestricted educational grant. Andrea Prader Prize The Andrea Prader Prize was first awarded 19 years ago and is named after the founder of paediatric endocrinology in Europe. The Prize recognises and rewards outstanding leadership and scientific contributions through the course of a career. The prize also draws attention to contributions to training in paediatric endocrinology. The 2007 Andrea Prader Prize has been awarded to Martin Savage. Professor Martin Savage began his studies in medicine in 1962 at Magdalene College in Cambridge and obtained his degree in 1968. From September 1975 to June 1977 he was Clinical Research Fellow in Paediatric Endocrinology at Hôpital Saint Vincent-de-Paul in Paris, France. His first papers were published in the early 1970s and were devoted to endocrine disorders in children. During the following 25 years Professor Savage's scientific interests focused particularly on disorders of growth and puberty. At present Martin Savage is both Professor of Paediatric Endocrinology and Head of Paediatric Endocrinology Section at Queen Mary's, University of London, UK. Martin Savage has been an ESPE member for almost 30 years. He has served the Society as Chair of several committees and as Secretary General from 1997 to 2004. More recently he has chaired the ESPE Corporate Liaison Board for more than 2 years. Research Award The Research Award is given to an ESPE member in recognition of clinical and/or basic scientific achievements that have made an important contribution to paediatric endocrinology The 2007 winner of the Research Award is Professor Primus Mullis from Bern, Switzerland. Primus Mullis is Professor of Paediatric Endocrinology, Diabetology and Metabolism at the University of Bern and Head of the Division of Paediatric Endocrinology, Diabetology and Metabolism at the University Children's Hospital in Bern. He graduated in medicine in 1981. From 1988 to 1990 he was a Research Fellow for Medical Molecular Biology and Paediatric Endocrinology at University College and Middlesex Medical School of Medicine, London. Honorary Senior Registrar and Honorary Research Fellow in Endocrinology and Metabolism at the John Radcliffe Hospital, University of Oxford, UK. Professor Mullis has been an ESPE officer for the past 5 years and chairperson of ESPE Research Unit since 2005. Outstanding Clinician Award This award is given each year to an ESPE member who has made an outstanding contribution as a clinical paediatric endocrinologist and has shown particular dedication and commitment throughout their career to the care of children with endocrine disorders. The winner of the Outstanding Clinician Award in 2007 was Catherine Dacou-Voutetakis. Professor Dacou-Voutetakis graduated from the University Medical School in Athens, Greece. She then trained in Paediatrics and Paediatric Endocrinology in the United States. Her paediatric endocrine training involved working with A M DiGeorge on a project investigating congenital absence of the thymus and its immunologic consequences (DiGeorge Syndrome). Back in Greece, Catherine Dacou-Voutetakis was appointed to the University School of Medicine in Athens. She became an ESPE member in 1973, was an ESPE council member from 1977 to 1980 and in 1978, as ESPE President, organized the Annual ESPE Meeting in Athens. She was appointed President of the Hellenic Endocrine Society in 1984 and is a founding member of the Hellenic Diabetes Association. In 1995 Professor Dacou-Voutetakis founded the Hellenic Society for Paediatric and Adolescent Endocrinology and was the Society's President for 3 years. In 1985 she organized the support group 'Galen' for children and adolescents with endocrine disorders and diabetes, which holds yearly seminars for patients and their parents.
Young Investigator Award The Young Investigator Award was established in recognition of scientific publications produced by an investigator working in Europe, who is not older than 40 years of age by the end of the year in which the award is presented. The 2007 Young Investigator Award has been awarded to Dr Antje Körner, from Leipzig, Germany. Dr Körner is an extremely talented young paediatric endocrinologist and has already published several papers in internationally ranked journals. She has investigated and demonstrated the interaction of adipose tissue in obesity related disease starting from the differentiation dependent expression of adipocytokines in vitro, to the development or growth related adipocytokine serum levels in children in vivo, the early derangement of adipocytokine levels in obese children, their clinical associations and consequences, and, finally, biological actions of adipocytokines at the cellular level
Henning Andersen Prizes Generously supported by Novo Nordisk, these two awards are given to the most highly rated clinical and experimental abstracts submitted to the Society's Annual Meeting. The prizes in basic and clinical science are awarded to abstracts on the basis of the reviewer ranking. The prize for the best basic science abstract submitted for the 2007 ESPE meeting went to the abstract entitled ‘SF1 mutations are a frequent cause in 46,XY patients with ambiguous genitalia due to impaired testicular androgen synthesis without adrenal insufficiency’, by Dr Birgit Köhler et al. from Charite, Children's Hospital, Pediatric Endocrinology, Berlin, Germany. Other authors include Lin Lin, Vanessa Schröder, Heike Biebermann, Peter Heidemann, Peter Wieacker, Olaf Hiort, Annette Grüters and John Achermann. The prize for the best clinical science abstract submitted for the 2007 ESPE meeting went to the abstract entitled ‘Generalized glucocorticoid insensitivity: clinical phenotype and molecular mechanisms’, by Dr Evangelia Charmandari et al. from the Section on Pediatric Endocrinology at the NIH in Bethesda, USA. Other authors include Tomoshige Kino, Takamasa Ichijo and George Chrousos. Hormone Research Prizes The Hormone Research Prizes are sponsored by Karger and are awarded to the best original paper published and the best paper published in the ‘Novel Insights from Clinical Experience’ section. The prize for the best original paper has been awarded to the manuscript ‘Insulin Resistance Is an Intrinsic Defect Independent of Fat Mass in Women with Turner’s Syndrome’, 2006, B Salgin, R Amin, K Yuen, RM Williams, P Murgatroyd & DB Dunger (Hormone Research 65 69-75). The prize for the best paper published in the ‘Novel Insights from Clinical Experience’ section has been awarded to the manuscript ‘Importance of Genetic Diagnosis of DAX-1 Deficiency: Example from a Large, Multigenerational Family’, 2006, S Ostermann, R Salvi, M Lang-Muritano, M-J Voirol, R Puttinger, RC Gaillard, E Schoenle & FP Pralong (Hormone Research 65 163-168).
Elections for a number of positions were held at the annual business meeting in Helsinki. Franco Chiarelli was re-elected as Secretary General. Stefano Cianfarani was re-elected as chair of the CPC, Moshe Phillip elected as chair of the ETC and Jean-Claude Carel as chair of the POC. Congratulations to all! ESPE Africa calls for volunteers Tertiary facilities and trained personnel for paediatric diabetes and other endocrine diseases are virtually non-existent in Africa. Responding to the need to put in place programs that address the care for children with endocrine diseases in Africa, a joint project of ESPE and three paediatric departments in Nairobi, Kenya aims at training African paediatricians to recognize and treat these diseases. The University of Nairobi, Department of Paediatrics and Child Health, Kenyatta National Referral Hospital, Aga Khan University Hospital and Gertrude's Children's Hospital in partnership with ESPE has initiated a fellowship program for paediatricians in Africa to enhance access to care and treatment. During the project period of 3 years, ESPE tutors will live in for 1-2 months at a time and fellows will have a training period of 12 months, including 9 months on site. The volunteering ESPE members will train the fellows to become accomplished experts in paediatric endocrinology and diabetes. During the 3-year project period, 3 Kenyan fellows will train to become the permanent faculty of an ongoing fellowship program after we leave. The programme has been granted €297000 from the World Diabetes Foundation (WDF). ESPE members who wish to take part in this programme between January 2008 to December 2010 are asked to make contact with Ze'ev Hochberg at z_hochberg@rambam.health.gov.il and indicate their preference of time and length of stay
ESPE Working Group Updates
As previously announced, the Medical Nobel Council convenes a Nobel Conference close to Stockholm on 16-18 May, 2008, with the aim at bringing together top scientists in systems biology with top clinical scientists in the field of child health, in order to contemplate how we can best implement the recent findings in systems biology in the clinical approach to child health. The scientific committee selected three important areas of child health: Obesity, diabetes and child growth. Clinical scientists will start out each session by presenting the challenges to child health, and the basic scientists with profound knowledge in systems biology will present their views on how their methods can be used for solving the clinical problems. Although Nobel Conferences are closed meetings with only speakers and invited discussants attending, the organizing committee will invite about 10 paediatric endocrinologists with ongoing research in systems biology to present an abstract at this Nobel Conference. This is an invitation to young researchers in childhood obesity, childhood diabetes and child growth to submit an abstract that will compete for one of the10 slots for poster presentation and travel grant at this closed conference. Priority will be given to abstracts of high quality that utilizes systems biology to solve questions on these three topics. Abstract submission deadline specially extended to 15 November 2007. ZE'EV HOCHBERG, Z_HOCHBERG@RAMBAM.HEALTH.GOV.IL IMPORTANT We request that you kindly notify the ESPE Secretariat if your contact details change. Please email the ESPE Secretariat at espe@eurospe.org to confirm your latest email address. Thank you! ESPE Newsletter ESPE Secretariat © 2007 The European Society for Paediatric Endocrinology The views expressed by the contributors are not necessarily those of ESPE. Secretary General Francesco Chiarelli, MD, PhD Professor of Paediatrics and Paediatric Endocrinology, University Department of Paediatrics, Via dei Vestini, 5, I-66013 Chieti, Italy Tel: +39 0871 358015 - 574538; Fax +39 0871 574831; Email: chiarelli@unich.it Editor Professor Jesús Argente Hospital Universitario Infantil Niño Jesús Department of Endocrinology, Universidad Autonoma, Avda Menendez Pelayo, 65, MADRID, ES-28009, Spain. Email: argentefen@terra.es ESPE web site: www.eurospe.org Newsletter: Designed by subLime Published by BioScientifica Ltd Euro House, 22 Apex Court, Woodlands, Bradley Stoke, Bristol, BS32 4JT, UK www.bioscientifica.com BioScientifica is a subsidiary of the Society for Endocrinology 4 The ESPE Secretariat is managed by BioScientifica Limited. BioScientifica is headed by Managing Director Sue Thorn and Events and Secretariats Director Helen Gregson. Pauline Bertrand, BioScientifica's Secretariats Manager, oversees the day-to-day relationship with ESPE, liaising with the ESPE council and committee members as well as being the main point of contact for ESPE enquiries. She undertakes projects requested by the General Secretary, providing him with assistance and attending ESPE council and committee meetings. Helena Marciano handles membership renewals, payments and banking and deals with subscriptions to Hormone Research. Tom Parkhill holds a seat on the Corporate Liaison Board and deals with industry sponsors, Andrew Lowe sub-edits and co-ordinates publication of the ESPE Newsletter. ESPE Secretariat, BioScientifica Ltd Euro House, 22 Apex Court, Woodlands, Bradley Stoke, Bristol, BS32 4JT, UK Tel: +44 (0) 1454 642 246 Fax: +44 (0) 1454 642 222 Email: espe@eurospe.org ESPE activities ESPE 2007 President's Poster Award Winners A new award was presented to the best 5 posters during the last session of the meeting in Helsinki. This award is selected based on the scientific content and presentation style. The winners received a certificate, a Presidential gift and will be listed amongst the ESPE's annual award winners. The ESPE 2007 President's Poster Award Winners were: P02-185 Glucocorticoid receptor expression is decreased in granulocytes of sepsis patients. Erica van den Akker, The Netherlands P01-365 Developmental programming of hypothalamic regulation of energy balance by early postnatal food restriction in rats. Floor Remmers, The Netherlands P02-342 Extended endocrine phenotype of NKX2.1 deficiency. Sarah Schnittert, Germany P01-526 Nutrition induced catch-up growth increases hypoxia inducible factor 1aRNA levels. Naomi Even-Zohar, Israel P01-529 Tamoxifen induces growth retardation in young intact male rats. Elham Karimian, Sweden
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