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ESPE Research Unit

The ESPE Research Unit is a collaborative research grant which aims to foster, facilitate, coordinate and identify topics for high quality research in paediatric endocrinology, for both physicians and scientists.

Grant Information

  • The ESPE Research Unit is open to ESPE members who intend to support collaborative research among members. Grant applications must have a designated principal investigator and at least two co-investigators who are ESPE members. Non-ESPE members may participate as additional co-investigators. 
  • One large grant and one small grant annually. The larger grant of €130,000 is for a period of two years (up to €65,000 per year) and the smaller grant of €15,000 is awarded for a period of one year.
  • The large grant covers salary, materials and consumables, small items of equipment, collaborative visits and overheads that should be less than 10% of the total value. The small grant does not cover salary.

The ESPE Research Unit is supported by an unrestricted grant from Sandoz.

Applications for 2018 are now closed. Details of the 2019 grant will be available in due course.

Eligibility

Specific Requirements
  • The principal investigator and at least two co-investigators should be ESPE members. Non-ESPE members may participate as additional co-investigators.
  • Majority of the research should be performed at the investigators' centre.
  • Beneficiaries of the Research Unit Grant may not hold more than one Research Unit Grant at any one time. This does not apply to non-beneficiaries.  
  • Current members of the Science Committee and ESPE Council are not eligible to apply for this grant as a co-investigator who is a financial beneficiary of the grant.
  • ESPE Research Unit awards can only be submitted by ESPE members who intend to support collaborative research among members.
  • A grant must be activated within 6 months of receipt.

Selection Criteria

The applications will be scored based on the following criteria:
  • Applicant CV
  • Host CV and institution (if applicable)
  • Focus and quality of application
  • Hypothesis
  • Methodology and experimental design
  • Potential for publication and further research
  • Timing and feasibility
  • Budget justification
  • Benefit for applicant and home institution
  • Relevance of the topic

Evaluation

Evaluation Procedure

The application and evaluation procedures take place in two stages:

  • All preliminary applications will be assessed for eligibility by the ESPE Research Unit Convenor.
  • All applications that fulfill the criteria of the grant will be invited to submit a final application.
  • All final applications will be subjected to a peer review by at least three experts that will include in the field on the Science Committee Expert Panel and external reviewers.
  • The ESPE Research Unit Convenor will select the external expert reviewers from the scientific community. 
  • Ranking is made by each reviewer independently based on the named selection criteria. The highest ranked projects are granted the award after approval by the ESPE Science Committee.
  • The ESPE Science Committee reserves the rights to withhold the award if the applications are deemed poor in quality.

How to Apply

A preliminary application should be completed and submitted before the preliminary deadline. All applications that fulfill the criteria of the grant will be invited to submit a final application before the final deadline.

If you have been invited to submit a final application, the following documents should be submitted by the application deadline. 

Applications must be submitted to the ESPE Team

Post Award Information

The forms below are for recipients of this grant only. A grant payment form and grant accountability report should be completed each time a payment is being requested. A grant report should be submitted 12 months into the grant and within 3 months of completion of the grant. Please note that the ESPE Research Unit must be acknowledged in any publications arising from the research. Papers published in connection with this research and any manuscripts in press should be submitted with the Final Report.

Applications must be submitted to the ESPE Team

2017-2019 ESPE Research Unit Grant

"Personalized approach to non-syndromic childhood obesity using multi-omics disease signature"

Investigators: Aneta Gawlik (Poland), Ze’ev Hochberg (Israel), Stefan A. Wudy (Germany), Michael Shmoish (Israel), Malgorzata Wasniewska (Italy), Abdullah Bereket (Turkey) 

 

"Comparison of the short and medium term side effects of first bisphosphonate infusion between children with different underlying bone pathologies."

Investigators: Moira Cheung (UK), Wolfgang Högler (UK), Oliver Semler (Germany), Adalbert Raimann (Austria) 

 

2016–2018 ESPE Research Unit Grant

"Improvement of Diagnostic workup for congenital hypothyroidism by a multigene NGS panel: A multicenter study to compare diagnostic accuracy and cost effectiveness"

Investigators: Gabor Szinnai , Johnny Deladoëy , Michel Polak, Heiko Krude, Paul van Trotsenburg, Switzerland, Canada, France, Germany, Netherland

 

"Identification of novel genetic causes of familial central precocious puberty"

Investigators: Magdalena Stefanija Avbel, Liat de Vries,Taneli Raivio, Slovenia, Israel, Finland

 

"YESS! Introduction of the Young Endocrine Support System in the transition from paediatric to adult endocrine care"

Investigators: Laura de Graaff, Sabine Elisabeth Hannema, Martine Cools, Gary Butler, Jesus Argente, Netherland, Belgium, UK, Spain

 

2015–2016 ESPE Research Unit Grant

"In search for novel monitoring tools to detect chronic over- or under-treatment in children with CAH"

Investigators: E van den Akker, E. Charmandari, C. Flueck. Netherland, Greece, Switzerland

 

2014–2016 ESPE Research Unit Grant

"Cellular Modelling of Human Gonad Sex-Determination"

Investigators: Anu Bashamboo, Ken McElreavey, Raja Brauner. Andy Greenfield, Radha Saraswathy, Faisal Ahmed. France, UK, India

 

"Managing clitoromegaly in childhood in girls with CAH: an investigation of the psychological impact of current treatment strategies"

Investigators: Elisabeth Crowne, Julie Alderson, Naomi Crouch, Faisal Ahmed, Bristol, Glasgow, UK

 

2014–2015 ESPE Research Unit Small Grant

"Overnight Glucose Control with MD-Logic Artificial Pancreas System in Young Children with Type 1 Diabetes"

Investigators: Susan M O'Connell, Amir Shafat, Bruce King, Ireland, Australia

 

2012–2014 ESPE Research Unit Grant

"Understanding the molecular basis of diabetes mellitus associated with novel syndromes."

Investigators: K Hussain, K Raile, F Darendeliler. United Kingdom, Germany, Turkey

 

"The impact of obesity on the molecular mechanisms involved in the development of metabolic abnormalities in children and adolescents."

Investigators: B Spiliotis, W Kiess, J Argente. Greece, Germany, Spain

 

2011–2012 ESPE Research Unit Grant

"New Genes for Neonatal Diabetes (ND) and Hyperinsulinemic Hypoglycemia (HH)."

Investigators: F Barbetti, RW Holl, CG Nichols. Italy, Germany, USA

 

"Study of early endocrine profile in infants with Prader-Willi syndrome (PWS) in order to unravel the switch from early feeding difficulties to obesity and hyperphagia."

Investigators: M Tauber, A Hokken–Koelaga, B Hauffa, A Goldstone V Beauloye, R Nergardh. France, Netherland, Germany, United Kingdom, Belgium, Sweden

 

"Abnormal Thyroid Development: a Model Disorder for Congenital Malformations and Neurocognitive Development."

Investigators: J Deladoey, M Polak, S Costagliola, G Van Vliet. Canada, France, Belgium

 

"EuroPHPnet, a unique tool to decipher the Gsa dependent signalling pathways."

Investigators: A Linglart, C Silve, O Hiort, S Thiele, S Fischer, L De Sanctis, A Spada, G Perez De Nanclares, K Freson. France, Germany, Italy, Spain, Belgium

 

2010–2011 ESPE Research Unit Small Grant

No grant was given

 

2010–2012 ESPE Research Unit Grant

"Infant manifestations of adult obesity susceptibility genotypes"

Investigators: K. Ong, B. Heude, L. Ibáñez, D. Dunger, MA Charles, F. de Zegher; from UK, France, Spain, Belgium

 

2009–2011 ESPE Research Unit Grant

"Effects of endocrine disrupting chemicals (EDC) on GnRH neuronal function."

Investigators: S Heger, A–S Parent, V Prevot; from Germany, Belgium, France

 

"Congenital Hyperinsulinism: Genes, phenotype and treatment."

Investigators: HB Christesen, V Peterkova, AN AlMutair, K Brusgaard; from Denmark, Russia, Saudi Arabia

 

2008–2010 ESPE Research Unit Grant

"Anti–Müllerian hormone levels in girls with Turner's syndrome: A possible predictor of ovarian function."

Investigators: CE Flück, JA Visser, MB Ranke, A Hokken-Koelege; from Switzerland, The Netherlands, Germany

 

2008–2009 ESPE Research Unit Small Grant

"Safety and Appropriateness of Growth Hormone treatments in Europe (SAGHE)"

Investigators: JC Carel; S Cianfarani, G Butler, L Savendahl; from France, Italy, UK, Sweden

 

"Endocrine and Genetic Characteristics of the Pygmy Population in South Western Uganda"

Investigators: Z Hochberg, E Mworozi, C Camacho-Hübner, M. Dattani; from Israel, Uganda, Sweden, UK

 

2007–2009 ESPE Research Unit Grant

"Molecular regulation of normal thyroid development and function and their diseases"

Investigators: M Polak, G. Szinnai, J. Moreno; from France, Switzerland, Netherlands

 

"Investigation of mitochondrial function and alterations in the mitochondrial proteome during development of obesity"

Investigators: AN Eberle, P Liniger, IM Fearnley, JE Walker, R Peterli, T Peters, U Zumsteg, J Mayr; from Switzerland, England

 

2007–2008 ESPE Research Unit Small Grant

"Identification of ABCC8 mutations in atypical type 1 diabetes patients and possible treatment consequences"

Investigators: PR Njølstad, A Molven, HB Mortensen, L Castaño; from Norway, Denmark, Spain

 

2006–2008 ESPE Research Unit Grant

"Exploring the utility of a European register of disorders of sex development / DSD"

Investigators: SF Ahmed, O Hiort, S Bertelloni, IA Hughes, SLS Drop, K Robertson, from Scotland, England, Germany, Italy, Netherlands

 

2006–2007 ESPE Research Unit Small Grant

No grant was given

 

2005–2007 ESPE Research Unit Grant

"Molecular regulation of the growth plate"

Investigators: J M Wit, L Sävendahl and G Rappold from The Netherlands, Sweden and Germany

 

2005–2006 ESPE Research Unit Small Grant

"Networking in Paediatric Endocrine Disruptors"

Investigators: J Toppari, J Anders, O Söder, JP Bourguignon, I Hughes, C Acerini, C Sultan from Finland, Denmark, Sweden, Belgium, United Kingdom, France

 

2004–2006 ESPE Research Unit Grant

"Screening and characterisation of DAX1–Interacting Proteins"

Investigators: A Tiulpakov, P Rubtson, W Sippell, N Krone and J Achermann from Russian Federation, Germany and United Kingdom.

 

2004–2005 ESPE Research Unit Small Grant

"Effects ACE-inhibitors on endothelial dysfunction and markers of angiopathy and oxidative stress in adolescent and young adults with type 1 diabetes"

Investigators: Angelika Mohn, M Vanelli, T Danne and H. Mortensen from Italy, Germany and Denmark

 

2003–2005 ESPE Research Unit Grant

"Rickets in Children of Middle Eastern Origin"

Investigators: G Saggesse, G Baroncelli, L Audi, A Bereket, H Delemarre–van de Waal, M El Kholy, Z Hochberg, E Schonau, N Shaw from Italy, Spain, Turkey, The Netherlands, Egypt, Israel, Germany and United Kingdom.

 

2002 ESPE Research Unit Small Grant

"The role of the Ihh/PTHrP feedback loop in the human growth plate: A concerted European action"

Investigators: L Sävendahl. JM Wit, H Robson, GR Williams, P Moshe, I Hughes, T Siebler, M Corvol, S van Buul-Offers from Sweden, The Netherlands, United Kingdom, Israel, and Germany.

 

2001–2003 ESPE Research Unit Grant

"Collaborative international studies on the long term effects of Prenatal Treatment of Congenital Adrenal Hyperplasia (PREDEX)"

Investigators: M Ritzén, A Wedell, S Lajic, R Voutilainen, K Main, M Ginalska–Malinowska, C Brain, P Hindmarsh, L Ibañez, M Forest from Sweden, Finland, Poland, Denmark, United Kingdom, Spain and France.