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View the 2018 Scientific Programme

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This day

07:30 - 20:30 
Registration
08:00 - 10:00 
ESPE Working Group on Disorders of Sex Development (DSD) & Turner Syndrome (TS)
ESPE DSD and TS Joint Meeting: Common ground of DSD and TS
Christos Lambrakis Hall
Chairs: Tülay Güran (Istanbul, Turkey), Malcolm Donaldson (Glasgow, UK), Rodolfo Rey (Buenos Aires, Argentina) & Christina Kanaka-Gantenbein (Athens, Greece)
08:00
Christos Lambrakis Hall
Session starts at 08:00
Introduction
Janielle van Alfen-van der Velden & Christa Flück (Nijmegen, The Netherlands & Bern, Switzerland)

08:03
Christos Lambrakis Hall
Session starts at 08:00
Session 1: Mixed gonadal dysgenesis
Tülay Güran (Istanbul, Turkey) & Malcolm Donaldson (Glasgow, UK)

08:05
Christos Lambrakis Hall
Session starts at 08:00
WG1.1
Longterm outcome in males with 45,X/46,XY mosaicism
Marie Lindhardt Ljubicic (Presented by Ewa Rajpert-De Meyts) (Copenhagen, Denmark)

08:25
Christos Lambrakis Hall
Session starts at 08:00
WG1.2
The 45X/46XY gonad and similar variants – characteristics and risk of malignancies
Ewa Rajpert-De Meyts (Copenhagen, Denmark)

08:50
Christos Lambrakis Hall
Session starts at 08:00
Session 2: Introduction
Rodolfo Rey (Buenos Aires, Argentina) & Christina Kanaka-Gantenbein (Athens, Greece)

08:52
Christos Lambrakis Hall
Session starts at 08:00
WG1.3
Congenital heart defects and cardiovascular risk in individuals who have a 45X/46XY karyotype
Katya De Groote (Ghent, Belgium)

09:45
Christos Lambrakis Hall
Session starts at 08:00
WG1.5
DSD News: I-DSD, I-CAH; DSDnet, Endo-ERN
Faisal Ahmed & Olaf Hiort (Glasgow, UK & Lubeck, Germany)

09:52
Christos Lambrakis Hall
Session starts at 08:00
WG1.6
TS News
Malcolm Donaldson (Glasgow, UK)

09:59
Christos Lambrakis Hall
Session starts at 08:00
Closing Remarks
Janielle van Alfen-van der Velden & Christa Flück (Nijmegen, The Netherlands & Bern, Switzerland)

08:00 - 10:00 
ESPE Working Group on Obesity
Lessons of metabolism in childhood obesity
Dimitris Mitropoulos Hall
Chairs: Jesús Argente (Madrid, Spain) & Tatyana Chaychenko (Kharkiv, Ukraine)
08:00
Dimitris Mitropoulos Hall
Session starts at 08:00
WG2.1
Body shapes - growth phenotypes in obese children
Antje Körner (Leipzig, Germany)

08:30
Dimitris Mitropoulos Hall
Session starts at 08:00
WG2.2
Impaired fasting glycaemia in pediatric obesity and type 2 diabetes in young adulthood
Claude Marcus (Stockholm, Sweden)

09:00
Dimitris Mitropoulos Hall
Session starts at 08:00
WG2.3
Less Prenatal and/or More Postnatal Weight Gain: a Highway to PCOS
Francis De Zegher (Leuven, Belgium)

09:30
Dimitris Mitropoulos Hall
Session starts at 08:00
WG2.4
Effects of the fetal-neonatal environment on later metabolism.
Julie A. Chowen (Madrid, Spain)

08:00 - 10:00 
ESPE Working Group on Bone and Growth Plate (BGP)
A Concise Update from the European Reference Networks & BGP case studies
Alexandra Trianti Hall
Chair: Ola Nilsson (Stockholm, Sweden), Oliver Semler (Cologne, Germany)
08:05
Alexandra Trianti Hall
Session starts at 08:00
WG3.1
Assessment of fracture risk in children
Amaka Offiah (Sheffield, UK)

08:35
Alexandra Trianti Hall
Session starts at 08:00
WG3.2
SHOX – from gene to growth plate
Gudrun Rappold (Heidelberg, Germany)

09:10
Alexandra Trianti Hall
Session starts at 08:00
WG3.3
Complex Clinical Presentations: Case Study 1:Dysosteosclerosis: Phenotypic and Genetic Heterogeneity
Serap Turan (Istanbul, Turkey)

09:40
Alexandra Trianti Hall
Session starts at 08:00
WG3.5
Update on EndoERN
Agnès Linglart (Paris, France)

09:50
Alexandra Trianti Hall
Session starts at 08:00
WG3.6
Update on BOND
Nick Bishop (Sheffield, UK)

08:00 - 10:00 
ESPE Working Group on Diabetes Technology (DT)
Digital Clinics
Banqueting Hall
Chairs: Moshe Phillip (Petah Tikva, Israel) & Tadej Battelino (Ljubljana, Slovenia)
08:00
Banqueting Hall
Session starts at 08:00
WG4.1
Introduction
Moshe Phillip (Petah Tikva, Israel)

08:25
Banqueting Hall
Session starts at 08:00
WG4.3
Use of Apps for Physical activity in type 1 diabetes
Olga Kordonouri (Hannover, Germany)

09:05
Banqueting Hall
Session starts at 08:00
WG4.5
Analyzing and Reporting of Sensor Glucose Levels
Revital Nimri (Petah Tikva, Israel)

09:25
Banqueting Hall
Session starts at 08:00
WG4.6
Updates on the developments of Decision Support Systems for the treatment of diabetes
Moshe Phillip (Petah Tikva, Israel)

09:45
Banqueting Hall
Session starts at 08:00
WG4.7
Use of social media for improving glucose control in patients with type 1 diabetes
Goran Petrovski (Skopje, Macedonia)

08:00 - 10:00 
Working Group: Paediatric and Adolescent Gynaecology (PAG)
Understanding the mechanisms related to pubertal onset and progression as well as the consequences of early puberty
Nikos Skalkotas Hall
Chairs: Anne-Simone Parent (Liège, Belgium) & Abel López-Bermejo (Girona, Spain)
08:00
Nikos Skalkotas Hall
Session starts at 08:00
WG5.1
Prenatal Programming of PCOS: interplay between anti-müllerian hormone and the GnRH system
Paolo Giacobini (Lille, France)

08:25
Nikos Skalkotas Hall
Session starts at 08:00
WG5.2
Genetic determinants of puberty timing
Ken Ong (Cambridge, UK)

08:45
Nikos Skalkotas Hall
Session starts at 08:00
WG5.3
Body adiposity as a determinant of age at puberty
Frank Biro (Cincinnati , USA)

09:10
Nikos Skalkotas Hall
Session starts at 08:00
WG5.4
Endocrine-metabolic outcome of women with a history of sexual precocity
Liat de Vries (Petah Tikva, Israel)

09:30
Nikos Skalkotas Hall
Session starts at 08:00
WG5.5
Neurodevelopment and puberty
Anne-Lise Goddings (London, UK)

08:00 - 10:00 
Working Group: Gender Dysphoria
Non-binary gender indentification & fertility in transgender adolescents
MC3
Chair: Gary Butler (London, UK)
08:00
MC3
Session starts at 08:00
Section 1: Non-binary gender identification; Social and endocrine management challenges

08:30
MC3
Session starts at 08:00
Endocrine challenges in adolescents with non-binary gender identification.
Panel and submitted case-presenting participants

09:00
MC3
Session starts at 08:00
Section 2: Fertility in transgender adolescents

09:05
MC3
Session starts at 08:00
WG6.2
Current options for fertility conservation in trans-teenagers
Ephia Yasmin (London, UK)

08:00 - 10:00 
Global Pediatric Endocrinology and Diabetes (GPED)
The art of pediatric endocrine testing: Assessing the needs of low-resource settings
MC2
08:00
MC2
Session starts at 08:00
Introduction
Dr Jean-Pierre Chanoine, (Vancouver, Canada)

08:05
MC2
Session starts at 08:00
The 2018 World Health Organization Model List of Essential In Vitro Diagnostics
Dr Julia von Oettingen, (Montreal, Canada)

08:25
MC2
Session starts at 08:00
Diagnostic Endocrine Tests in Egypt and Indonesia: Opportunities and Obstacles
Dr Rasha T Hamza & Dr Aman Pulungan (Cairo, Egypt & Jakarta, Indonesia)

09:05
MC2
Session starts at 08:00
The WHO Model Lists of Essential Medicines and of In Vitro Diagnostics: Two Sides of the Same Coin?
Jean-Pierre Chanoine (Vancouver, Canada)

10:00 - 10:30 
Refreshment Break, Posters & Exhibition
10:30 - 10:45 
Opening Ceremony
Christos Lambrakis Hall
10:45 - 11:15 
Plenary 1
Christos Lambrakis Hall
Chairs: Peter Clayton (Manchester, UK) & Anita Hokken-Koelega (Rotterdam, The Netherlands)
10:45
Christos Lambrakis Hall
Session starts at 10:45
PL1
Oncofertility: From Bench to Bedside to Babies
Teresa Woodruff (Chicago, USA)

11:15 - 11:45 
ESPE AWARDS
Henning Andersen Prizes
Supported by Novo Nordisk
Christos Lambrakis Hall
Chair: Mehul T Dattani (London, UK)
12:00 - 13:30 
Special Symposium: Nutrition and Growth
Nikos Skalkotas Hall
Chairs: Moshe Phillip (Petah Tikva, Israel) & Jan-Maarten Wit (Leiden, Holland)
12:00
Nikos Skalkotas Hall
Session starts at 12:00
SS1.1
It is not just the growth hormone axis
Ola Nilsson (Stockholm, Sweden)

12:30
Nikos Skalkotas Hall
Session starts at 12:00
SS1.2
Fascinating growth phenomena: what causes individual catch-up growth and population secular change
Jan-Maarten Wit (Leiden, Holland)

13:00
Nikos Skalkotas Hall
Session starts at 12:00
SS1.3
Interaction between nutrition, the endocrine system and the growth plate
Moshe Phillip (Petah Tikva, Israel)

12:00 - 13:30 
Symposium 1
Recent developments in the understanding of Hypothalamo-pituitary disorders
Dimitris Mitropoulos Hall
Chairs: Roland Pfäffle (Leipzig, Germany) & Rachel Reynaud (Marseille, France)
12:00
Dimitris Mitropoulos Hall
Session starts at 12:00
S1.1
The molecular basis of Combined Pituitary Hormone Deficiency: lessons from animal models
Sally Camper (Michigan, USA)

12:30
Dimitris Mitropoulos Hall
Session starts at 12:00
S1.2
Stem Cells in the Pituitary: a role for regeneration?
Karine Rizzoti (London, UK)

13:00
Dimitris Mitropoulos Hall
Session starts at 12:00
S1.3
A novel role for Vasopressin in parenting
Andrés Bendesky (New York, USA)

12:00 - 13:30 
Symposium 2
Gonads/DSD
Banqueting Hall
Chairs: Christina Kanaka-Gantenbein (Athens, Greece) & Reiko Horikawa (Tokyo, Japan)
12:00
Banqueting Hall
Session starts at 12:00
S2.1
The biology of germ cell tumors in Disorders of Sex Development
Leendert Looijenga (Rotterdam, The Netherlands)

12:30
Banqueting Hall
Session starts at 12:00
S2.2
Disruption of testicular development and function
Rod Mitchell (Edinburgh, UK)

13:00
Banqueting Hall
Session starts at 12:00
S2.3
Assessing gonadal function
Anders Juul (Copenhagen, Denmark)

12:00 - 13:30 
Symposium 3
Recent Consensus Guidelines
Christos Lambrakis Hall
Chairs: Asma Deeb (Abu Dhabi, UAE) & Agnès Linglart (Paris, France)
12:00
Christos Lambrakis Hall
Session starts at 12:00
S3.1
Silver-Russell Syndrome
Irene Netchine (Paris, France)

12:20
Christos Lambrakis Hall
Session starts at 12:00
S3.2
Hypogonadotrophic Hypogonadism
Taneli Raivio (Helsinki, Finland)

12:40
Christos Lambrakis Hall
Session starts at 12:00
S3.3
Paediatric Obesity
Dennis Styne (Sacramento, USA)

13:00
Christos Lambrakis Hall
Session starts at 12:00
S3.4
Prevention and Management of Rickets
Wolfgang Hogler (Birmingham, UK)

12:00 - 13:30 
Controversy 1
Should growth hormone be used in iSS?
Alexandra Trianti Hall
Chair: Stefano Cianfarani (Rome, Italy)
12:00
Alexandra Trianti Hall
Session starts at 12:00
CON1.1
PRO - Should Growth Hormone be used in iSS?
Ron Rosenfeld (Oregon, USA)

12:45
Alexandra Trianti Hall
Session starts at 12:00
CON1.2
AGAINST - Should Growth Hormone be used in iSS?
Jean-Claude Carel (Paris, France)

13:30 - 15:00 
Lunch, Posters & Exhibition
14:00 - 15:00 
Satellite Symposia
Alexandra Trianti Hall
15:00 - 16:00 
Free Communications 1
Adrenals and HPA Axis
Christos Lambrakis Hall
Chairs: Svetlana Lajic (Stockholm, Sweden) & Stefan Wudy (Giessen, Germany)
15:00
Christos Lambrakis Hall
Session starts at 15:00
FC1.1
A novel non-invasive Short Synacthen Test validated in a healthy paediatric population.
Charlotte Elder (Sheffield, UK)

15:50
Christos Lambrakis Hall
Session starts at 15:00
FC1.6
A novel stem cell model for the Triple A Syndrome.
Alexandra Rodrigues Da Costa (London, UK)

15:00 - 16:00 
Free Communications 2
Bone, growth plate and mineral metabolism 1
Banqueting hall
Chairs: Nick Shaw (Birmingham, UK) & Lars Sävendahl (Stockholm, Sweden)
15:20
Banqueting hall
Session starts at 15:00
FC2.3
Clinical course of hypoparathyroidism in patients with APECED (APS1)
Saila Laakso (Helsinki, Finland)

15:30
Banqueting hall
Session starts at 15:00
FC2.4
Diagnostic Performance of Artificial Neural Network-Based TW3 Skeletal Maturity Assessment.
Xuelian Zhou (Hangzhou, China)

15:40
Banqueting hall
Session starts at 15:00
FC2.5
Radial ESWT stimulates longitudinal bone growth in cultured rat fetal metatarsal bones.
Sowmya Ramesh (Vellore, India)

15:50
Banqueting hall
Session starts at 15:00
FC2.6
Final Height is Negatively Related to Disease Burden in Mitochondrial Disease.
Rachel Boal (Newcastle Upon Tyne, UK)

15:00 - 16:00 
Free Communications 3
Diabetes and Insulin Session 1
Dimitris Mitropoulos
Chair: Hilary Hoey (Ireland) and Thomas Reinehr (Datteln, Germany)
15:00 - 16:00 
Free Communications 4
GH and IGFs
Nikos Skalkotas
Chairs: Feyza Darendeliler (Istanbul, Turkey) & Bradley Miller (Minnesota, USA)
15:00
Nikos Skalkotas
Session starts at 15:00
FC4.1
Monogenic and digenic gene mutations are present in children with idiopathic short stature (ISS).
Ana Claudia Keselman (Buenos Aires, Argentina)

15:10
Nikos Skalkotas
Session starts at 15:00
FC4.2
Effects of IGF-1R nuclear localization in glioblastoma cells.
Patricia Pennisi (Buenos Aires, Argentina)

15:50
Nikos Skalkotas
Session starts at 15:00
FC4.6
Absorption and Excretion of Somapacitan, a Long-Acting Growth Hormone (GH) Derivative.
Michael Højby Rasmussen (Søborg, Denmark)

15:00 - 16:00 
Free Communications 5
Thyroid
MC3
Chairs: Johnny Deladoey (Montreal, Canada) & Paul Von Trotsenberg (Amsterdam, The Netherlands)
15:30
MC3
Session starts at 15:00
FC5.4
Thyroid hormone analog therapy in patients with MCT8 deficiency: the Triac Trial.
Stefan Groeneweg (Rotterdam, The Netherlands)

15:00 - 16:00 
How do I...
Session 1
Alexandra Trianti Hall
Chair: Nils Krone (Sheffield, UK)
15:00
Alexandra Trianti Hall
Session starts at 15:00
HDI1.1
…Interpret a low Vit D concentration?
Raja Padidela (Manchester, UK)

15:20
Alexandra Trianti Hall
Session starts at 15:00
HDI1.2
…Differentiate between constitutional delay in growth and puberty and hypog hypog?
Gerhard Binder (Tubingen, Germany)

15:40
Alexandra Trianti Hall
Session starts at 15:00
HDI1.3
...Manage an adolescent with Type 1 diabetes and microalbuminuria
Carlo Acerini (Cambridge, UK)

16:00 - 16:30 
Rapid Free Communications 1
Adrenals and HPA axis
Christos Lambrakis Hall
Chairs: Svetlana Lajic (Stockholm, Sweden) & Stefan Wudy (Giessen, Germany)
16:00
Christos Lambrakis Hall
Session starts at 16:00
RFC1.1
The relative contributions of genetic and environmental factors on cortisol metabolism at pre-, mid- and post-pubertal ages.
Britt van Keulen (Amsterdam, The Netherlands)

16:05
Christos Lambrakis Hall
Session starts at 16:00
RFC1.2
Changes in CYP19A1 and CYP3A4 activities due to population genetic variations in human P450 Oxidoreductase.
Shaheena Parween (Bern, Switzerland)

16:10
Christos Lambrakis Hall
Session starts at 16:00
RFC1.3
Sphingosine-1-phosphate lyase (SGPL1) deficiency is associated with mitochondrial dysfunction.
Avinaash Maharaj (London, UK)

16:15
Christos Lambrakis Hall
Session starts at 16:00
RFC1.4
Mass spectrometry-based assessment of childhood androgen excess in 487 consecutive patients over 5 years.
Jan Idkowiak (Birmingham, UK)

16:00 - 16:30 
Rapid Free Communications 2
Bone, growth plate and mineral metabolism 1
Banqueting hall
Chair: Nick Shaw (Birmingham, UK)
16:00 - 16:30 
Rapid Free Communications 3
Diabetes and Insulin Session 1
Dimitris Mitropoulos
16:00 - 16:30 
Rapid Free Communications 4
GH and IGFs
Nikos Skalkotas
Chairs: Feyza Darendeliler (Istanbul, Turkey) & Bradley Miller (Minnesota, USA)
16:00
Nikos Skalkotas
Session starts at 16:00
RFC4.1
Metabolomic changes in patients with PAPP-A2 deficiency in response to rhIGF1 treatment.
Jesús Argente (Madrid, Spain)

16:25
Nikos Skalkotas
Session starts at 16:00
RFC4.6
Effect of 2 years of Growth Hormone Treatment on Glucose Tolerance in Adults with Prader-Willi Syndrome.
Layla Damen (Rotterdam, The Netherlands)

16:00 - 16:30 
Rapid Free Communications 5
Thyroid
MC3
Chairs: Johnny Deladoey (Gatineau, Canada) & Paul Van Trotsenberg (Amsterdam, The Netherlands)
16:10
MC3
Session starts at 16:00
RFC5.3
Incidence and treatment outcome of childhood thyrotoxicosis.
Maria Lodefalk (Örebro, Sweden)

16:20
MC3
Session starts at 16:00
RFC5.5
Evidence for a founder effect in Multiple Endocrine Neoplasia 2.
Vassos Neocleous (Nicosia, Cyprus)

16:30 - 16:45 
Refreshment Break, Posters & Exhibition
16:45 - 17:15 
Plenary 2.
Christos Lambrakis Hall
Chairs: Mehul T Dattani (London, UK) & George Chrousos (Athens, Greece)
16:45
Christos Lambrakis Hall
Session starts at 16:45
PL2
Oxytocin and the healing power of love
Sue C Carter (Indiana, USA)

17:15 - 18:15 
Meet The Expert 1
Dimitris Mitropoulos Hall
17:15
Dimitris Mitropoulos Hall
Session starts at 17:15
MTE1.1
The role of Radiology in the diagnosis of skeletal dysplasias
Amaka Offiah & Nadia Amin (Sheffield, UK & Leeds, UK)

17:15 - 18:15 
Meet The Expert 2
Nikos Skalkotas Hall
17:15
Nikos Skalkotas Hall
Session starts at 17:15
MTE2.1
Endocrine complications in Thalassemia
Nicos Skordis & Andreas Kyriakou (Nicosia, Cyprus & Glasgow, UK)

17:15 - 18:15 
Meet The Expert 3
Banqueting Hall
17:15
Banqueting Hall
Session starts at 17:15
MTE3.1
Neuro endocrine assessment after a childhood intracranial or suprasellar tumour
Helen Spoudeas & Hoong-Wei Gan (London, UK & London, UK)

17:15 - 18:15 
Meet The Expert 4
Alexandra Trianti Hall
17:15
Alexandra Trianti Hall
Session starts at 17:15
MTE4.1
The use of modern technologies to optimise diabetes care
Olga Kordonouri (Hannover, Germany)

17:15 - 18:15 
Yearbook of Paediatric Endocrinology 1
Christos Lambrakis Hall
Chair: Juliane Léger (Paris, France)

Christos Lambrakis Hall
Session starts at 17:15
YB1.1
Thyroid
Gabor Szinnai (Basel, Switzerland)


Christos Lambrakis Hall
Session starts at 17:15
YB1.2
Adrenals
Evangelia Charmandari (Athens, Greece)


Christos Lambrakis Hall
Session starts at 17:15
YB1.3
Obesity and Weight Regulation
Martin Wabitsch (Ulm, Germany)


Christos Lambrakis Hall
Session starts at 17:15
YB1.4
Type 2 Diabetes, Metabolic Syndrome and Lipids
Orit Hamiel (Tel-Aviv, Israel)


Christos Lambrakis Hall
Session starts at 17:15
YB1.5
Global Health for the Paediatric Endocrinologist
Jean-Pierre Chanoine (Vancouver, Canada)

18:30 - 20:00 
Satellite Symposium
Alexandra Trianti Hall
18:30 - 20:00 
Satellite Symposium
Nikos Skalkotas Hall
18:30 - 20:00 
Satellite Symposium
Dimitris Mitropoulos Hall
20:00 - 21:30 
Informal ESPE Networking Event
Exhibition Hall