The annual ESPE-Hormone Research in Paediatrics award, initiated in 2004, rewards a young clinical or experimental scientist for the "best original paper" and "Novel Insights from Clinical Practice" published in Hormone Research in Paediatrics.

Nominations are closed.

The Editor-in-Chief and the Associate Editors of Hormone Research in Paediatrics makes up the Selection Committee and potential winners are elected in the Spring. The decision is notified to the authors by July.

The award is generously offered by the journal's publisher S. Karger. It is awarded at the ESPE Annual Meeting and given to the first author of the winning article.


Original paper:

Laetitia Martinerie et al

"Fertility of Women Treated during Childhood with Triptorelin (Depot Formulation) for Central Precocious Puberty: The PREFER Study"

Novel Insights from Clinical Practice:

Annalisa Deodati et al

"Crk Haploinsufficiency Is Associated with Intrauterine Growth Retardation and Severe Postnatal Growth Failure"

Previous Winners

Click to show previous winners


Original paper:

Letteria Anna Morabito et al

"Growth Trajectory and Adult Height in Children with Nonclassical Congenital Adrenal Hyperplasia"

Novel Insights from Clinical Practice:

Meera Shaunak etc al

"Isolated 17, 20 Lyase Deficiency Secondary to a Novel CYB5A Variant: Comparison of Steroid Metabolomic Findings with Published Cases Provides Diagnostic Guidelines and Greater Insight into its Biological Role"


Original paper:

Stanik J. et al

"The Bone Markers Sclerostin, Osteoprotegerin, and Bone-Specific Alkaline Phosphatase Are Related to Insulin Resistance in Children and Adolescents, Independent of Their Association with Growth and Obesity"

Novel Insights from Clinical Practice:

Rathi Prasad etc al

"Haploinsufficiency of NKX2-1 in Brain-Lung-Thyroid Syndrome with Additional Multiple Pituitary Dysfunction"


Original paper: Bonfig W., Roehl F., Riedl S., Bramswig J., Richter-Unruh A., Frick-Otto S., Hubner A., Bettendorf M., Schonau E., Dorr H., Holl R.W., Mohnike K.

"Sodium Chlorise Supplementation Is No Routinely Performed in the Majority of German and Austrian Infants with Classic Salt-Wasting Congenital Adrenal Hyperplasia and Has No Effect on Linear Growth and Hydrocortisone or Fludrocortisone Dose"

Novel Insights from Clinical Practice: Saraff V., Rothenbuhler A., Hogler W., Linglart A.

"Continuous Subcutaneous Recombinant Parathyroid Hormone (1-34) Infusion in the Management of Childhood Hypoparathyroidism Associated with Malabsorption"


Original paper: Osen S., Onay H., Atik T., Solmaz A.E., Ozkinay F., Goksen D., Darcan S.

"Rapid Molecular Genetic Diagnosis with Next-Generation Sequencing in 46,XY Disorders of Sex Development Cases: Efficiency and Cost Assessment"

Novel Insights from Clinical Practice: Sediva H., Dusatkova P., Kanderova V., Obermannova B., Kayserova J., Sramkova L., Zemkova D., Elblova L., Svaton M., Zachova R., Kolouskova S., Fronkova E., Sumnik Z., Sediva A., Lebl J., Pruhova S.

"Short Stature in a Boy with Multiple Early-Onset Autoimmune Conditions due to a STAT3 Activating Mutating: Could Intracellular Growth Hormone Signalling Be Compomised?"


Original paper: Bakker NEE., Siemensma EP., Koopman C., Hokken–Koelega AC.

"Dietary Energy Intake, Body Composition and Resting Energy Expenditure in Prepubertal Children with Prader–Willi Syndrome before and during Growth Hormone Treatment: A Randomized Controlled Trial"

Novel Insights from Clinical Practice: Saraco N., Nesi–Franca S., Sainz R., Marino R., Marques–Pereira R., La Pastina J., Perez Garrido N., Sandrini R., Rivarola M.A., de Lacerda L., Belgorosky A.

"An Intron 9 CYP19 Gene Variant (IVS9+5G>A), Present in an Aromatase-Deficient Girl, Affects Normal Splicing and Is Also Present in Normal Human Steroidogenic Tissues"


Original paper: de Jong M.; Lafeber H.N.; Cranendonk A.; van Weissenbruch M.M.

"Components of the Metabolic Syndrome in Early Childhood in Very–Low–Birth–Weight Infants"

Novel Insights from Clinical Practice: Busiah K.; Verkarre V.; Cavé H.; Scharfmann R.; Polak M.

"Human Pancreas Endocrine Cell Populations and Activating ABCC8 Mutations"


Original paper: Alexandra E. Kulle; Welzel, M.; Holterhus P.M.; Riepe, F.G.

"Implementation of a Liquid Chromatography Tandem Mass Spectrometry Assay for Eight Adrenal c–21 Steroids and Pediatric Reference Data"

Novel Insights from Clinical Practice: Julia von Schnurbein; Heni, M.; Moss, A.; Nagel, S.A.; Machann, J.; Muehleder, H.; Debatin, K.M.; Farooqi, S.; Wabitsch, M.

"Rapid Improvement of Hepatic Steatosis after Initiation of Leptin Substitution in a Leptin–Deficient Girl"


Original paper: Satu Pirilä, Saarinen-Pihkala, U.M.; Viljakainen, H.; Turanlahti, M.; Kajosaari, M.; Mäkitie, O.; Taskinen, M.

"Breastfeeding and determinants of adult body composition: a prospective study from birth to young adulthood"

Novel Insights from Clinical Practice: Julia von Schnurbein, Moss, A.; Nagel, S.A.; Muehleder, H.; Debatin, K.M.; Farooqi, I.S.; Wabitsch, M.

"leptin substitution results in the induction of menstrual cycles in an adolescent with leptin deficiency and hypogonadotrophic hypogonadism"


Original paper: Rikke Beck Jensen, Vielwerth, S.; Larsen, T.; Hilsted, L. Cohen, A.; Hougaard, D.M.; Jensen, L.T.; Greisen, G. and Juul, A. 

"Influence of Fetal Growth Velocity and Smallness at Birth on Adrenal Function in Adolescence"

Novel Insights from Clinical Practice: Tohru Yorifuji , Hosokawa, Y.; Fujimaru, R.; Kawakita, R.; Doi, H.; Matsumoto, T.; Nishibori, H.; Masue, M.

"Lasting 18F-DOPA PET Uptake after Clinical Remission of the Focal Form of Congenital Hyperinsulinism"


Original paper: Su-Jin Lee

"Estrogen Prevents Senescence through Induction of WRN, Werner Syndrome Protein"

Novel Insights from Clinical Practice: Anitha Kumaran

"Congenital Hyperinsulinism due to a Compound Heterozygous ABCC8 Mutation with Spontaneous Resolution at Eight Weeks"


Original Paper: Talia Eldar-Geva, Harry J. Hirsch, Ron Rabinowitz, Fortu Benarroch, Orit Rubinstein, Varda Gross-Tsur

Primary Ovarian Dysfunction Contributes to the Hypogonadism in Women with Prader-Willi Syndrome. Horm Res2009;72;153-159

Novel Insights from Clinical Practice: Jerzy Starzyk, Malgorzata Wójcik, Joanna Wojtys, Przemyslaw Tomasik, Zofia Mitkowska, Jacek J. Pietrzyk.

Ovarian Hyperstimulation Syndrome in Newborns - A Case Presentation and Literature Review. Horm Res. 2009;71:60-64


Best original paper: Eric Mallet, Rouen, France

Best paper published in the "Novel Insights": Klaus Mohnike, Magdeburg, Germany


Insulin Resistance is an Intrinsic Defect Independent of Fat Mass in Women with Turner's Syndrome

Burak Salgin, Rakesh Amin, Kevin Yuen, Rachel M. Williams, Peter Murgatroyd, David B. Dunger

Hormone Research 2006;65:69-75 (DOI: 10. 1159/000090907)

Importance of Genetic Diagnosis of DAX-1 Deficiency: Example from a Large, Multigenerational Family

Sandrine Ostermann, Roberto Salvia, Mariarosaria Lang-Muritano, Marie-Jeanne Voirol, Rudolf Puttinger, Rolf C. Gaillard, Eugen Schoenle, François P. Pralong

Hormone Research 2006;65:163-168 (DOI: 10. 1159/000091831)


Transactivation Properties of Wild-Type and Mutant Androgen Receptors in Transiently Transfected Primary Human Fibroblasts

P.M. Holterhus, J. Salzburg, R. Werner, O. Hiort

Hormone Research 2005;63:152-158 (DOI: 10. 1159/000085005)


Genotype-Phenotype Correlation in Patients Suspected of Having Sotos Syndrome

Lonneke de Boer, Sarina G. Kant, Marcel Karperien, Lotte van Beers, Jennifer Tjon, Geraldine R. Vink, Dewy van Tol, Hans Dauwerse, Saskia le Cessie, Frits A. Beemer, Ineke van der Burgt, Ben C.J. Hamel, Raoul C. Hennekam, Ursula Kuhnle, Inge B. Mathijssen, Hermine E. Veenstra-Knol, Connie T. Schrander Stumpel, Martijn H. Breuning, Jan M. Wit

Hormone Research 2004;62:197-207 (DOI: 10.1159/000081063)


IGF-I Transcript Levels in Whole-Liver Tissue, in Freshly Isolated Hepatocytes, and in Cultured Hepatocytes from Lean and Obese Zucker Rats

S. Tenoutasse, G. Van Vliet, E. Ledru, C. Deal

Hormone Research 2003;59:135-141 (DOI: 10. 1159/000069066)